Annual report pursuant to Section 13 and 15(d)

Stockholders' Equity (Details 4)

v3.8.0.1
Stockholders' Equity (Details 4) - $ / shares
 12 Months Ended
Dec. 31, 2017
Dec. 31, 2016
Weighted Average Remaining Contractural Life - Years 8 years 4 months 24 days 7 years 2 months 16 days
Number of options outstanding 3,976,884 2,172,581
Weighted Average Exercise Price Stock Options Outstanding $ 3.58 $ 6.70
Number of Awards Vested 2,434,148 1,722,105
Weighted Average Exercise Price $ 4.84 $ 7.03
Weighted Average Remaining Contractual Life of Stock Options Vested 7 years 8 months 12 days 6 years 5 months 16 days
Range One [Member]    
Exercise price lower range limit $ 1.05 $ 1.14
Exercise price upper range limit $ 2.00 $ 4.00
Weighted Average Remaining Contractural Life - Years 9 years 6 months 21 days 9 years 10 months 6 days
Number of options outstanding 2,528,666 678,769
Weighted Average Exercise Price Stock Options Outstanding $ 1.18 $ 1.55
Number of Awards Vested 1,197,708 678,769
Weighted Average Exercise Price $ 1.33 $ 1.55
Weighted Average Remaining Contractual Life of Stock Options Vested 9 years 3 months 11 days 9 years 10 months 6 days
Range Two [Member]    
Exercise price lower range limit $ 2.01 $ 4.01
Exercise price upper range limit $ 6.00 $ 6.00
Weighted Average Remaining Contractural Life - Years 7 years 10 months 10 days 8 years 10 months 10 days
Number of options outstanding 821,174 816,794
Weighted Average Exercise Price Stock Options Outstanding $ 4.59 $ 4.60
Number of Awards Vested 651,429 477,302
Weighted Average Exercise Price $ 4.58 $ 4.60
Weighted Average Remaining Contractual Life of Stock Options Vested 7 years 10 months 10 days 8 years 9 months 29 days
Range Three [Member]    
Exercise price lower range limit $ 6.01 $ 6.01
Exercise price upper range limit $ 20.00 $ 20.00
Weighted Average Remaining Contractural Life - Years 5 years 1 month 13 days 6 years 1 month 13 days
Number of options outstanding 505,694 505,694
Weighted Average Exercise Price Stock Options Outstanding $ 7.47 $ 7.47
Number of Awards Vested 463,661 394,710
Weighted Average Exercise Price $ 7.58 $ 7.36
Weighted Average Remaining Contractual Life of Stock Options Vested 4 years 11 months 4 days 5 years 10 months 28 days
Range Four [Member]    
Exercise price lower range limit $ 20.01 $ 20.01
Exercise price upper range limit $ 45.00 $ 45.00
Weighted Average Remaining Contractural Life - Years 1 year 7 months 28 days 2 years 2 months 27 days
Number of options outstanding 118,016 144,683
Weighted Average Exercise Price Stock Options Outstanding $ 29.85 $ 31.47
Number of Awards Vested 118,016 144,683
Weighted Average Exercise Price $ 29.85 $ 31.47
Weighted Average Remaining Contractual Life of Stock Options Vested 1 year 7 months 28 days 2 years 2 months 27 days
Range Five [Member]    
Exercise price lower range limit $ 45.01 $ 45.01
Exercise price upper range limit $ 72.00 $ 72.00
Weighted Average Remaining Contractural Life - Years 2 months 5 days 11 months 9 days
Number of options outstanding 3,334 26,641
Weighted Average Exercise Price Stock Options Outstanding $ 50.25 $ 53.03
Number of Awards Vested 3,334 26,641
Weighted Average Exercise Price $ 50.25 $ 53.03
Weighted Average Remaining Contractual Life of Stock Options Vested 2 months 5 days 11 months 9 days