Stockholders' Equity and Stock-Based Compensation (Tables)
|
3 Months Ended |
Mar. 31, 2019 |
Stockholders Equity And Stock-based Compensation |
|
Schedule of Warrants Outstanding |
|
|
March
31, |
|
|
December
31, |
|
Outstanding
Warrants |
|
2019 |
|
|
2018 |
|
Issued
to Investors on October 25, 2013, entitling the holders to purchase 250,000 common shares in the Company at an exercise price
of $11.50 per common share up to and including April 24, 2021. In 2016, 59,450 of these warrants were exchanged for common
stock, and all remaining warrant holders agreed to new warrant terms, which excluded any potential net cash settlement provisions
in exchange for a reduced exercise price of $6.25 per share. |
|
|
163,986 |
|
|
|
163,986 |
|
|
|
|
|
|
|
|
|
|
Issued
to Investors on November 17, 2014, entitling the holders to purchase 546,919 common shares in the Company at an exercise price
of $11.55 per common share up to and including May 16, 2022. On June 30, 2016, the warrant holders agreed to new warrant terms,
which excluded any potential net cash settlement provisions in order to classify them as equity in exchange for a reduced
exercise price of $6.25 per share. |
|
|
546,919 |
|
|
|
546,919 |
|
|
|
|
|
|
|
|
|
|
Issued
to an investment bank and subsequently transferred to a principal of the investment bank regarding the Series B Preferred
Stock investment on January 30, 2018, entitling the holder to purchase 133,432 common shares in the Company at an exercise
price of $1.50 per share, up to and including January 30, 2021. |
|
|
133,432 |
|
|
|
133,432 |
|
|
|
|
|
|
|
|
|
|
Total |
|
|
844,337 |
|
|
|
844,337 |
|
|
Schedule of Share-based Compensation, Stock Options, Activity |
|
|
Three
Months ended
March
31,
|
|
|
|
2019 |
|
|
2018 |
|
|
|
|
|
|
|
|
Research
and development expenses |
|
$ |
170,134 |
|
|
$ |
503,217 |
|
General
and administrative expenses |
|
|
164,879 |
|
|
|
769,818 |
|
Total
stock-based compensation expense |
|
$ |
335,013 |
|
|
$ |
1,273,035 |
|
|
Schedule of weighted average years remaining of expected life activity |
Expected
volatility |
|
|
90 |
% |
Risk
free interest rate |
|
|
2.84 |
% |
Dividend
yield rate |
|
|
0 |
% |
Weighted
average years |
|
|
9.8 months |
|
Closing
price per share – common stock |
|
$ |
0.88 |
|
|
Schedule of Stock option transactions of the employees |
Stock
option transactions to the employees, directors and consultants are summarized as follows for the three months ended March 31,
2019:
|
|
Options
Outstanding
|
|
|
Weighted
Average
Exercise
Price
|
|
|
Weighted
Average
Grant
Date
Fair
Value
|
|
Beginning
of the period |
|
|
5,604,154 |
|
|
$ |
2.72 |
|
|
$ |
1.96 |
|
Granted
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
Exercised
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
Forfeited
|
|
|
(215,598 |
) |
|
|
2.44 |
|
|
|
1.75 |
|
Expired
|
|
|
(46,364 |
) |
|
|
19.10 |
|
|
|
18.47 |
|
End
of the period |
|
|
5,342,192 |
|
|
$ |
2.59 |
|
|
$ |
1.82 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Options
exercisable |
|
|
3,673,176 |
|
|
$ |
3.36 |
|
|
$ |
2.34 |
|
Stock
option transactions of the employees, directors, and consultants are summarized as follows for the year ended December 31, 2018:
|
|
Options
Outstanding
|
|
|
Weighted
Average
Exercise
Price
|
|
|
Weighted
Average
Grant
Date
Fair
Value
|
|
Beginning
of the year |
|
|
3,976,884 |
|
|
$ |
3.58 |
|
|
$ |
2.49 |
|
Granted
|
|
|
1,784,455 |
|
|
|
0.90 |
|
|
|
0.70 |
|
Exercised
|
|
|
- |
|
|
|
- |
|
|
|
- |
|
Forfeited
|
|
|
(143,980 |
) |
|
|
1.10 |
|
|
|
0.83 |
|
Expired
|
|
|
(13,205 |
) |
|
|
30.60 |
|
|
|
21.13 |
|
End
of the year |
|
|
5,604,154 |
|
|
$ |
2.72 |
|
|
$ |
1.96 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Options
exercisable |
|
|
3,935,138 |
|
|
$ |
3.50 |
|
|
$ |
2.49 |
|
|
Schedule of Non-Vested Options, Activity |
|
|
Shares |
|
|
Weighted-
Average
Fair
Value
Grant
Date
|
|
|
Weighted
Average
Exercise
Price
|
|
|
|
|
|
|
|
|
|
Non-vested
– December 31, 2017 |
|
|
1,542,736 |
|
|
$ |
1.10 |
|
|
$ |
1.58 |
Granted
|
|
|
1,784,455 |
|
|
|
0.70 |
|
|
|
0.90 |
Vested
|
|
|
(1,514,195 |
) |
|
|
1.27 |
|
|
|
1.58 |
Forfeited
|
|
|
(143,980 |
) |
|
|
0.83 |
|
|
|
1.10 |
Non-vested
– December 31, 2018 |
|
|
1,669,016 |
|
|
$ |
0.54 |
|
|
$ |
0.91 |
|
|
|
|
|
|
|
|
|
|
|
|
Granted
|
|
|
- |
|
|
|
- |
|
|
|
- |
Vested
|
|
|
- |
|
|
|
- |
|
|
|
- |
Forfeited
|
|
|
- |
|
|
|
- |
|
|
|
- |
Non-vested
– March 31, 2019 |
|
|
1,669,016 |
|
|
$ |
0.54 |
|
|
$ |
0.91 |
|
Schedule of Disclosure of Share-based Compensation Arrangements by Share-based Payment Award |
The
following table provides certain information with respect to the above-referenced stock options that were outstanding and exercisable
at March 31, 2019:
|
|
Stock
Options Outstanding |
|
|
Stock
Options Vested |
|
|
|
Weighted |
|
|
|
|
|
|
|
|
Weighted |
|
|
|
|
|
|
|
|
|
Average |
|
|
|
|
|
|
|
|
Average |
|
|
|
|
|
|
|
|
|
Remaining |
|
|
|
|
|
Weighted |
|
|
Remaining |
|
|
|
|
|
Weighted |
|
|
|
Contractual |
|
|
Number |
|
|
Average |
|
|
Contractual |
|
|
Number |
|
|
Average |
|
|
|
Life |
|
|
of |
|
|
Exercise |
|
|
Life |
|
|
of |
|
|
Exercise |
|
Exercise
Prices |
|
|
-Years |
|
|
Awards |
|
|
Price |
|
|
|
-Years |
|
|
Awards |
|
|
Price |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
$0.90-$1.04 |
|
|
9.35 |
|
|
|
1,616,402 |
|
|
$ |
0.90 |
|
|
|
- |
|
|
|
- |
|
|
$ |
- |
|
$1.05-$2.00 |
|
|
8.32 |
|
|
|
2,397,193 |
|
|
$ |
1.18 |
|
|
|
8.31 |
|
|
|
2,344,579 |
|
|
$ |
1.19 |
|
$2.01-$6.00 |
|
|
6.61 |
|
|
|
787,760 |
|
|
$ |
4.59 |
|
|
|
6.61 |
|
|
|
787,760 |
|
|
$ |
4.59 |
|
$6.01-$20.00 |
|
|
3.95 |
|
|
|
465,850 |
|
|
$ |
7.49 |
|
|
|
3.95 |
|
|
|
465,850 |
|
|
$ |
7.49 |
|
$20.01-$43.25 |
|
|
0.79 |
|
|
|
74,987 |
|
|
$ |
32.87 |
|
|
|
0.79 |
|
|
|
74,987 |
|
|
$ |
32.87 |
|
Total |
|
|
7.89 |
|
|
|
5,342,192 |
|
|
$ |
2.59 |
|
|
|
7.24 |
|
|
|
3,673,176 |
|
|
$ |
3.36 |
|
The
following table provides certain information with respect to the above-referenced stock options that were outstanding and exercisable
at December 31, 2018:
|
|
Stock
Options Outstanding |
|
|
Stock
Options Vested |
|
|
|
Weighted |
|
|
|
|
|
|
|
|
Weighted |
|
|
|
|
|
|
|
|
|
Average |
|
|
|
|
|
|
|
|
Average |
|
|
|
|
|
|
|
|
|
Remaining |
|
|
|
|
|
Weighted |
|
|
Remaining |
|
|
|
|
|
Weighted |
|
|
|
Contractual |
|
|
Number |
|
|
Average |
|
|
Contractual |
|
|
Number |
|
|
Average |
|
|
|
Life |
|
|
of |
|
|
Exercise |
|
|
Life |
|
|
of |
|
|
Exercise |
|
Exercise
Prices |
|
|
-Years |
|
|
Awards |
|
|
Price |
|
|
|
-Years |
|
|
Awards |
|
|
Price |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
$0.90-$1.04 |
|
|
9.60 |
|
|
|
1,616,402 |
|
|
$ |
0.90 |
|
|
|
— |
|
|
|
- |
|
|
$ |
— |
|
$1.05-$2.00 |
|
|
8.57 |
|
|
|
2,560,330 |
|
|
$ |
1.18 |
|
|
|
8.56 |
|
|
|
2,507,716 |
|
|
$ |
1.18 |
|
$2.01-$6.00 |
|
|
6.86 |
|
|
|
813,583 |
|
|
$ |
4.59 |
|
|
|
6.86 |
|
|
|
813,583 |
|
|
$ |
4.59 |
|
$6.01-$20.00 |
|
|
4.16 |
|
|
|
501,334 |
|
|
$ |
7.48 |
|
|
|
4.16 |
|
|
|
501,334 |
|
|
$ |
7.48 |
|
$20.01-$43.25 |
|
|
0.72 |
|
|
|
112,505 |
|
|
$ |
29.46 |
|
|
|
0.72 |
|
|
|
112,505 |
|
|
$ |
29.46 |
|
Total |
|
|
8.07 |
|
|
|
5,604,154 |
|
|
$ |
2.72 |
|
|
|
7.42 |
|
|
|
3,935,138 |
|
|
$ |
3.50 |
|
|